What is the genotype for normal male hemophilia?
Expression and Transmission
What is the genotype of a man with normal blood clotting whose father had hemophilia?
Since this is a recessive disorder, one XH allele will give a normal phenotype. When the offspring do not have a XH and only have the Xh allele/alleles they will have the hemophilia condition. Man’s genotype is XhY.
How many alleles do males have for blood clotting?
There are no genes for clotting factors on the Y chromosome. This means that males only have one allele for factor VIII and one allele for factor IX. Thus, if a male has a hemophilia allele on his only X chromosome, he will have the disorder.
What is the hemophilia genotype?
The abnormal gene responsible for hemophilia is carried on the X chromosome. Males have one X chromosome and one Y chromosome. In a male, the presence of the abnormal gene results in the deficiency or absence of factor VIII or factor IX, as there is no protective X to make factor VIII or IX.
What is the genotype for males?
The X and Y chromosomes, also known as the sex chromosomes, determine the biological sex of an individual: females inherit an X chromosome from the father for a XX genotype, while males inherit a Y chromosome from the father for a XY genotype (mothers only pass on X chromosomes).
What is the genotype of the male answer?
When a sperm carrying the Y chromosome fertilizes an egg, the resulting embryo has a genotype of XY and will be a male.
What are the heterozygous genotypes?
(HEH-teh-roh-ZY-gus JEE-noh-tipe) The presence of two different alleles at a particular gene locus. A heterozygous genotype may include one normal allele and one mutated allele or two different mutated alleles (compound heterozygote).
Is PP genotype or phenotype?
There are three available genotypes, PP (homozygous dominant ), Pp (heterozygous), and pp (homozygous recessive). All three have different genotypes but the first two have the same phenotype (purple) as distinct from the third (white).
Is von Willebrand a disease?
Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. Blood contains many proteins that help the blood clot when needed. One of these proteins is called von Willebrand factor (VWF).
What is the correct genotype of the woman?
Using the definition of “genotype” that refers to a relevant section of the DNA sequence inherited by an organism, the genotype of female humans is XX, as opposed to male humans’ genotype XY.
Do females have more possible genotypes than males?
A male has different genotype possibilities than a female. Since he has only one X chromosome (paired with a Y), he will have only one copy of any X-linked genes.
What is Haemophilia B?
Hemophilia B is a hereditary bleeding disorder caused by a lack of blood clotting factor IX. Without enough factor IX, the blood cannot clot properly to control bleeding.
What is the genotype of the mother?
The mothers genotype is AO. The fathers genotype is BO. The genotypes of each child is OO for the child with type O blood and BO for the child with…
Is Hemophilia A genotype or phenotype?
Haemophilia was previously regarded as a classical example of Mendelian inheritance, with mutation in only a single gene (F8 or F9) causing the disease phenotype. The disease manifests complete penetrance. Studies, however, revealed the striking genetic and phenotypic heterogeneities of the disease.