Eighty percent of children with either trisomy 21 or mosaicism Down syndrome are born to mothers who are younger than 35 years old. Younger women have babies more frequently, so the number of babies with Down syndrome are higher in that group.
What type of people are affected by Down syndrome?
Down syndrome occurs in people of all races and economic levels, though older women have an increased chance of having a child with Down syndrome. A 35 year old woman has about a one in 350 chance of conceiving a child with Down syndrome, and this chance increases gradually to 1 in 100 by age 40.
What race is affected by Down syndrome?
Down syndrome has been reported in people of all races; no racial predilection is known. African American patients with Down syndrome have substantially shorter life spans than white patients with trisomy 21.
Who is more likely to have a Down syndrome child?
According to the Centers for Disease and Prevention, mothers aged 35 and older are more likely to have a baby with Down syndrome than younger mothers. The probability increases the older the mother is.
What ethnicity has the highest rate of Down syndrome?
In a comparison of quinquennial maternal age-specific risk rates of Down syndrome by race, Hispanics and whites were the only groups with rates that differed significantly from each other, with Hispanics exhibiting higher rates at maternal ages under 40 years.
What age group is affected by Down syndrome?
Women who are 35 years or older when they become pregnant are more likely to have a pregnancy affected by Down syndrome than women who become pregnant at a younger age. However, the majority of babies with Down syndrome are born to mothers less than 35 years old, because there are many more births among younger women.
How does Down syndrome affect someone?
An individual with Down syndrome inherits all or part of an extra copy of Chromosome 21. Symptoms associated with the syndrome include mental retardation, distinctive facial characteristics, and increased risk for heart defects and digestive problems, which can range from mild to severe.
Is Down syndrome passed genetically?
Most of the time, Down syndrome isn’t inherited. It’s caused by a mistake in cell division during early development of the fetus. Translocation Down syndrome can be passed from parent to child.
What race has the most birth defects?
American Indians had the highest rates of lethal birth defects, followed by Asians, Hispanics, and blacks. The variation in rate of lethal birth defects among racial/ethnic groups may have been related to both incidence and survival.
Is Down syndrome common in Africa?
Study objective: Down syndrome (DS), the commonest cause of congenital developmental disability in developed countries, has only recently been shown to have an incidence in black South African neonates as high, and in some studies higher, than currently seen in First-World nations.
Does Down syndrome affect males or females more?
Overall, the two sexes are affected roughly equally. The male-to-female ratio is slightly higher (approximately 1.15:1) in newborns with Down syndrome, but this effect is restricted to neonates with free trisomy 21.
Can 2 Down syndrome parents have a normal child?
Parents with one baby with regular trisomy 21 are usually told that the chance of having another baby with Down’s syndrome is 1 in 100. Very few families are known who have more than one child with Down’s syndrome, so the real chance is probably less than this.
How is the family of a person with Down syndrome affected?
Like any child, those children with Down syndrome in cohesive and harmonious families were also less likely to have behavior problems and more likely to have higher levels of functioning. Mothers expressing poor relationships with the child and family were more likely to have high stress scores.
What country has the most Down syndrome cases?
These population figures mean that for every 10,000 people there are 5.14 people with Down syndrome. This is similar to other countries like the UK. Down syndrome is the most commonly occurring chromosomal condition. It is estimated that approximately 1 in every 1100 babies born in Australia will have Down syndrome.
What percentage of population has Down syndrome?
Most recently, Parker et al1 studied the prevalence of Down syndrome births in data from 24 birth defects programs accounting for 32.3% of total US births, and estimated it as 14.47 per 10 000 live births.
Are mixed race babies more likely to have birth defects?
Conclusions. Mixed race black and white couples face higher odds of prematurity and low birth weight, which appear to contribute to the substantially higher demonstrated risk for stillbirth. There are likely additional unmeasured factors that influence birth outcomes for mixed race couples.