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The Hardy-Weinberg equation is a mathematical equation that can be used to calculate the genetic variation of a population at equilibrium. … If the p and q allele frequencies are known, then the frequencies of the three genotypes may be calculated using the Hardy-Weinberg equation.

## Why does the Hardy-Weinberg equation really matter?

Despite the reality of such factors in almost every real population, the Hardy-Weinberg equation remains so important to biology because it establishes the null hypothesis against which those factors are tested by biologists.

## How does the Hardy-Weinberg equation work?

The Hardy-Weinberg equation used to determine genotype frequencies is: p^{2} + 2pq + q^{2} = 1. Where ‘p^{2}‘ represents the frequency of the homozygous dominant genotype (AA), ‘2pq’ the frequency of the heterozygous genotype (Aa) and ‘q^{2}‘ the frequency of the homozygous recessive genotype (aa).

## Why is Hardy-Weinberg equilibrium not realistic?

The Hardy-Weinberg equilibrium can be disrupted by deviations from any of its five main underlying conditions. Therefore mutation, gene flow, small population, nonrandom mating, and natural selection will disrupt the equilibrium.

## Why is the Hardy Weinberg principle useful to biologists quizlet?

Why is the Hardy−Weinberg principle useful when studying population genetics? It explains how alleles and genotypes behave in a nonevolving population, because the Hardy-Weinberg principle gives biologists a baseline to evaluate whether or not evolution is occurring in a population.

## Why is 2pq not PQ?

Note that the heterozygotes are not 2pq but pq because in each case they are only being considered for the one allele in question. If we scale all wii’s such that the largest = 1.0 we refer to these as the relative fitnesses of the genotypes. A worked example where p = . 4, q = .

## How does the Hardy-Weinberg equation show evolution?

There are five basic Hardy-Weinberg assumptions: no mutation, random mating, no gene flow, infinite population size, and no selection. If the assumptions are not met for a gene, the population may evolve for that gene (the gene’s allele frequencies may change).

## Why does the Hardy-Weinberg equation not generally apply to real world populations?

Hi Andrei, The HW equilibrium is used as a null hypothesis; genotypes occur in predicable frequencies and allele frequencies do not change over time. Hence, (generically) evolution is not occurring.