Translocations. A translocation occurs when a piece of one chromosome breaks off and attaches to another chromosome. This type of rearrangement is described as balanced if no genetic material is gained or lost in the cell.
When one piece of a chromosome breaks off and is transferred to a nonhomologous chromosome?
If a chromosome break occurs in each of two nonhomologous chromosomes and the two breaks rejoin in a new arrangement, the new segment is called a translocation.
Which type of chromosomal mutation has occurred when a chromosome piece breaks off and reattaches to another nonhomologous chromosome?
A translocation occurs when a segment of a chromosome dissociates and reattaches to a different, nonhomologous chromosome. Translocations can be benign or have devastating effects, depending on how the positions of genes are altered with respect to regulatory sequences.
Which chromosomal defect is caused when part of a chromosome breaks off at either end and attaches to another chromosome quizlet?
Translocation is a type of chromosomal abnormality in which a chromosome breaks and a portion of it reattaches to a different chromosome. Chromosomal translocations can be detected by analyzing karyotypes of the affected cells.
What type of mutation is it when a piece breaks off and reattaches to the sister chromatid?
When part of a chromatid breaks off and attaches to its sister chromatid, an insertion occurs.
When a piece of a chromosome breaks off and is re inserted such that the alleles are in reverse order?
An inversion is a chromosome rearrangement where a single chromosome undergoes breakage and is then reversed and rearranged within itself. Inversions are of two types: paracentric and pericentric.
What is chromosome deletion?
Deletion. = Deletion is a type of mutation involving the loss of genetic material. It can be small, involving a single missing DNA base pair, or large, involving a piece of a chromosome.
What is an example of an insertion mutation?
Insertion mutations occur when extra genetic material is added to a DNA sequence.
Examples of Diseases Caused by Insertion Mutations.
|Myotonic dystrophy||Over 50 repeats of CTG in a gene on chromosome 19||Muscle weakness and atrophy|
What is a fragmented chromosome?
Chromosome fragmentation is a major form of mitotic cell death that is identified through abnormal cytogenetic figures [4,13]. These figures contain chromosomes with multiple breaks, similar to the morphology of S-phase PCC which is discussed below.
When does translocation occur?
Translocations occur when chromosomes become broken during meiosis and the resulting fragment becomes joined to another chromosome. Reciprocal translocations: In a balanced reciprocal translocation (Fig. 2.3), genetic material is exchanged between two chromosomes with no apparent loss.
When part of a chromosome is transferred from one chromosome to a non homologous chromosome a <UNK> mutation results?
Translocations generate novel chromosomes. In a translocation, a segment from one chromosome is transferred to a nonhomologous chromosome or to a new site on the same chromosome. Translocations place genes in new linkage relationships and generate chromosomes without normal pairing partners.
Which type of chromosomal mutation causes this form of Down syndrome quizlet?
About 95 percent of the time, Down syndrome is caused by trisomy 21 — the person has three copies of chromosome 21, instead of the usual two copies, in all cells. This is caused by abnormal cell division during the development of the sperm cell or the egg cell.
Which type of mutation causes this translation error that leads to cystic fibrosis quizlet?
Cystic fibrosis is caused by various mutations? in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene? on chromosome? 7. The most common genetic abnormality causing cystic fibrosis involves the deletion of just three DNA bases (a codon?) from the CFTR gene.
What are the 4 types of chromosomal mutations give examples of each?
deletion is where a section of a chromosome is removed. translocation is where a section of a chromosome is added to another chromosome that is not its homologous partner. inversion is where a section of a chromosome is reversed. duplication occurs when a section of a chromosome is added from its homologous partner.
What are the 4 types of chromosomal mutations?
As mentioned above, the four types of Chromosomal Mutations I are inversion, deletion, duplication/amplification, and translocation. All four of these can be seen in Figure 3 above. These mutations alter the structure of the chromosome since they tend to break and these pieces often form sticky ends.
What is gene mutation and how do mutations occur?
A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is copied or as the result of environmental factors such as UV light and cigarette smoke. Mutations can occur during DNA replication if errors are made and not corrected in time.