Individuals with DS have higher rates of thyroid dysfunction. Abnormalities include subclinical hypothyroidism (SCH; also referred to as hyperthyrotropinemia), congenital hypothyroidism (CH), and thyroid autoimmunity such as Hashimoto’s Disease (HD) or Grave’s Disease (GD).
How does Down syndrome affect the hormone system?
Hypothyroidism is also common in adults with Down syndrome and can lead to symptoms of fatigue, mental sluggishness, weight fluctuations and irritability. Studies of adults with Down syndrome vary widely, but the incidence of thyroid disease in adults with Down syndrome is believed to be between 13% and 50%.
Is Down syndrome a hormonal disease?
Children with Down syndrome, or Trisomy 21, have a higher likelihood of developing endocrine disorders than the general population. Hypothyroidism is the most common endocrine disorder in Down syndrome. About 10 percent of children with Down syndrome are diagnosed with congenital or acquired hypothyroidism.
What can affect the hormonal system?
Some of the factors that affect endocrine organs include puberty, aging, pregnancy, the environment, genetics and certain diseases and medications, including naturopathic medicine, herbal supplements, and prescription medicines such as opioids or steroids.
What is the endocrine disorder in this individual?
Common endocrine disorders include diabetes mellitus, acromegaly (overproduction of growth hormone), Addison’s disease (decreased production of hormones by the adrenal glands), Cushing’s syndrome (high cortisol levels for extended periods of time), Graves’ disease (type of hyperthyroidism resulting in excessive thyroid …
Can hypothyroidism cause Down syndrome in pregnancy?
The observation that thyroid disease is frequent in mothers of children with Down syndrome (DS) has suggested that maternal thyroid antibodies could be a factor predisposing to trisomy 21 in their offspring.
Is Down syndrome life threatening?
These complications can include: Heart defects. About half the children with Down syndrome are born with some type of congenital heart defect. These heart problems can be life-threatening and may require surgery in early infancy.
What’s the cause of hypothyroidism?
The most common cause of hypothyroidism is an autoimmune disorder known as Hashimoto’s thyroiditis. Autoimmune disorders occur when your immune system produces antibodies that attack your own tissues. Sometimes this process involves your thyroid gland.
What causes congenital hypothyroidism in newborns?
The most common cause worldwide is a shortage of iodine in the diet of the mother and the affected infant. Iodine is essential for the production of thyroid hormones. Genetic causes account for about 15 to 20 percent of cases of congenital hypothyroidism.
What causes hormonal changes?
The main causes of hormonal imbalances are issues with the thyroid, stress, and eating disorders. Some symptoms include irregular periods, low sex-drive, unexplained weight gain, and mood swings. Your hormones, which your endocrine system makes, are your body’s messengers.
What are 5 functions of hormones?
They control a number of functions including metabolism, reproduction, growth, mood, and sexual health. If your body is producing too little or too much of a hormone, it can make you very ill and set you up for a number of serious health problems.
What are hormonal factors?
The term female hormonal factors encompass reproductive characteristics or events associated with changes in serum sex hormone levels, mainly oestrogens and progesterone, that women experience throughout their lifetime [22, 23].
What will be the result of the endocrine system failed to release hormones?
Without your endocrine glands — and the hormones they release — your cells wouldn’t know when to do important things. For instance, your bones wouldn’t get the message that it’s time for you to grow and get bigger.
Can hormone imbalance cause neurological symptoms?
Endocrine dysfunctions may lead to various neurologic manifestations such as headache, myopathy, and acute encephalopathy including coma. It is important to recognize the neurologic signs and symptoms caused by the endocrine disorders while managing endocrine disorders.
Which signs or symptoms would result from syndrome of inappropriate antidiuretic hormone?
Symptoms of syndrome of inappropriate antidiuretic hormone include water retention and low sodium level. Low sodium levels may cause lethargy and confusion. Severe low levels of sodium in the body may cause muscle twitching, seizures , stupor, coma, and death.