Which type of chromosomal mutation causes this form of Down syndrome *?
2: Trisomy 21 (Down Syndrome) Karyotype. A karyotype is a picture of a cell’s chromosomes. Note the extra chromosome 21.
Which type of chromosomal mutation causes Klinefelter syndrome quizlet?
If an egg cell with an extra X chromosome (XX) is fertilized by a sperm cell with one Y chromosome, the resulting child will have Klinefelter syndrome.
Which type of chromosomal mutation causes Klinefelter syndrome Nondisjunction?
Klinefelter’s syndrome, XXY males, can occur due to nondisjunction of X chromosomes during prophase of meiosis I in females. One of the eggs from such a meiosis could receive both X chromosomes, and the other would receive no X chromosomes.
Which is a frameshift mutation?
A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three.
How does translocation cause Down syndrome?
Translocation Down syndrome happens when an extra copy of chromosome 21 is attached to another chromosome. This is then present in all cells of the body. Chromosomes contain all of the genetic information that tells our body how to grow and function.
What causes Klinefelter syndrome meiosis?
In 1959, Klinefelter syndrome was found to be caused by a supernumerary X chromosome in a male. The 47,XXY karyotype of Klinefelter syndrome spontaneously arises when paired X chromosomes fail to separate (nondisjunction in stage I or II of meiosis, during oogenesis or spermatogenesis).
Which is an agent that causes a mutation in DNA or chromosomes?
A mutagen is defined as an agent that causes irreversible and heritable changes (mutations) in the cellular genetic material, deoxyribonucleic acid (DNA).
Which of the following is an example of a Klinefelter syndrome?
Males who have Klinefelter syndrome may have the following symptoms: small, firm testes, a small penis, sparse pubic, armpit and facial hair, enlarged breasts (called gynecomastia), tall stature, and abnormal body proportions (long legs, short trunk).
What type of mutation is Klinefelter syndrome?
Klinefelter syndrome can be caused by: One extra copy of the X chromosome in each cell (XXY), the most common cause. An extra X chromosome in some of the cells (mosaic Klinefelter syndrome), with fewer symptoms. More than one extra copy of the X chromosome, which is rare and results in a severe form.
What causes Down syndrome?
About 95 percent of the time, Down syndrome is caused by trisomy 21 — the person has three copies of chromosome 21, instead of the usual two copies, in all cells. This is caused by abnormal cell division during the development of the sperm cell or the egg cell.
What is Down syndrome chromosome?
Typically, a baby is born with 46 chromosomes. Babies with Down syndrome have an extra copy of one of these chromosomes, chromosome 21. A medical term for having an extra copy of a chromosome is ‘trisomy. ‘ Down syndrome is also referred to as Trisomy 21.
Is Down Syndrome a chromosomal mutation?
Down syndrome is a genetic disease resulting from a chromosomal abnormality. An individual with Down syndrome inherits all or part of an extra copy of Chromosome 21.
What are 5 types of chromosomal mutations?
- Non-Disjunction and Down’s Syndrome.
- Inversion of Genes.
- Translocation of Genes.
What causes chromosomal mutation?
Chromosome structure mutations are alterations that affect whole chromosomes and whole genes rather than just individual nucleotides. These mutations result from errors in cell division that cause a section of a chromosome to break off, be duplicated or move onto another chromosome.