Repetitive regions at the very ends of chromosomes are called telomeres, and they’re found in a wide range of eukaryotic species, from human beings to unicellular protists. Telomeres act as caps that protect the internal regions of the chromosomes, and they’re worn down a small amount in each round of DNA replication.
What is the function of telomerase in DNA replication quizlet?
telomerase adds DNA nucleotides to the overhang and DNA polymerase extends the complimentary strand.
Why are telomeres so important in the replication of DNA quizlet?
Why are telomeres important? They stabilize the ends of chromosomes.
What are the telomeres and why are they important?
Telomeres, the specific DNA–protein structures found at both ends of each chromosome, protect genome from nucleolytic degradation, unnecessary recombination, repair, and interchromosomal fusion. Telomeres therefore play a vital role in preserving the information in our genome.
What is the role of telomeres quizlet?
What is the function of the telomere? Telomeres prevent the ends of chromosomes from being damaged. Telomeres prevent the shortening of chromosomes during replication and the accidental fusion of two chromosomes at their ends.
What are telomeres and what happens to them during DNA replication quizlet?
Telomeres are the ends of DNA. Long-repeated strands added to deal with end-replication problem. … The RNA in telomeres serves as a template (150nt long). Stem cells and cancer cells express telomerase.
What role do telomeres play in eukaryotic DNA replication in germ cells quizlet?
So telomeres allow cells to divide without losing genes. Cell division is necessary for growing new skin, blood, bone, and other cells. Without telomeres, chromosome ends could fuse together and corrupt the cell’s genetic blueprint, possibly causing malfunction, cancer, or cell death.
When telomeres become very short the cell quizlet?
Each time a cell divides, some of the telomere is lost (usually 25-200 base pairs per division). When the telomere becomes too short, the chromosome reaches a “critical length” and can no longer replicate. This means that a cell becomes “old” and dies by a process called apoptosis.
What would happen if telomerase stopped working?
Without telomerase activity, these cells would become inactive, stop dividing and eventually die. Drugs that inhibit telomerase activity, or kill telomerase-producing cells, may potentially stop and kill cancer cells in their tracks.
What would happen if telomerase stopped working in a cell in which it normally functions at high levels?
What would happen if telomerase stopped working in a cell in which it normally functions at high levels? … The cell would eventually die as the DNA continued to shorten.
Why do we need telomerase?
Telomeres act as protective caps on the ends of our chromosomes and prevent damage and fusion with other chromosomes. A useful analogy for this can be the way an aglet of a shoelace prevents fraying, unravelling and tangling of laces.
What is the role of telomeres in aging?
Telomeres play a central role in cell fate and aging by adjusting the cellular response to stress and growth stimulation on the basis of previous cell divisions and DNA damage. At least a few hundred nucleotides of telomere repeats must “cap” each chromosome end to avoid activation of DNA repair pathways.
How do telomeres prevent the loss of genetic material?
To prevent the loss of genes as chromosome ends wear down, the tips of eukaryotic chromosomes have specialized DNA “caps” called telomeres. Proteins associated with the telomere ends also help protect them and prevent them from triggering DNA repair pathways. …
Which of the followings are the roles of telomeres?
Telomeres represent ends of all eukaryotic chromosomes and serve specialized biological role in maintaining genomic integrity by preventing end fusions and degradation. Various protein complexes associate with telomeres to either protect them from DNA damage machinery or maintain telomere length homeostasis.
Which of the following are functions of telomeres?
They function to protect the ends of chromosomes from sticking to each other. They also protect genetic information during cell division because a short piece of each chromosome is lost every time DNA is replicated. Cells use a special enzyme called telomerase to keep dividing, which lengthens their telomeres.
What are telomeres and what two protective functions do they serve quizlet?
What are the two protective functions of a telomere? 1) Proteins associated with telomeric DNA prevent the ends of the daughter molecule from activating the cell’s systems for monitoring cell damage. 2) Provides protection agains the organism’s genes shortening.