Almost one-half of babies with Down syndrome have congenital heart disease (CHD), the most common type of birth defect.
What disease category is Down syndrome?
Down syndrome or Down’s syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is usually associated with physical growth delays, mild to moderate intellectual disability, and characteristic facial features.
What are 4 common congenital anomalies of a child with Down syndrome?
The most common associated anomalies were cardiac anomalies, 323 cases (44%), followed by digestive system anomalies, 42 cases (6%), musculoskeletal system anomalies, 35 cases (5%), urinary system anomalies, 28 cases (4%), respiratory system anomalies, 13 cases (2%), and other system anomalies, 26 cases (3.6%).
What are the disabilities of Down syndrome?
Down syndrome is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone (hypotonia) in infancy. All affected individuals experience cognitive delays, but the intellectual disability is usually mild to moderate.
What is considered high risk for Down syndrome?
Patients are more likely to have a baby with Down syndrome or another chromosome abnormality when they are age 35 or older, or if they have already had a child with such an abnormality. These patients are considered “high-risk” and have additional testing options.
Is Down syndrome recessive or dominant?
Like cystic fibrosis, Down’s Syndrome is autosomal recessive. This means that the condition is genetic and passed down by the mother and/or the father but the condition is not shown in the parents. An autosomal recessive disorder requires two copies of the abnormal gene for the disease or trait to develop.
Is Down syndrome inheritable?
Most of the time, Down syndrome isn’t inherited. It’s caused by a mistake in cell division during early development of the fetus. Translocation Down syndrome can be passed from parent to child.
What body systems are affected by Down syndrome?
Down syndrome, the most common chromosome-related genetic condition in the U.S., affects development of the brain and body. People with Down syndrome face physical and mental challenges, but can lead full and happy lives.
Is Down syndrome congenital or genetic?
Down syndrome, also called Down’s syndrome, trisomy 21, or (formerly) mongolism, congenital disorder caused by the presence in the human genome of extra genetic material from chromosome 21.
Is Down syndrome a congenital anomaly?
The most common, severe congenital anomalies are heart defects, neural tube defects and Down syndrome. Although congenital anomalies may be the result of one or more genetic, infectious, nutritional or environmental factors, it is often difficult to identify the exact causes.
Can a person with Down syndrome play sports?
While most children with Down Syndrome learn to walk, many struggle with higher level physical activities that require more coordination and dexterity. Because of this, they may be inclined to shy away from sports.
Does Down syndrome run in the family?
Does Down Syndrome Run in Families? All 3 types of Down syndrome are genetic conditions (relating to the genes), but only 1% of all cases of Down syndrome have a hereditary component (passed from parent to child through the genes). Heredity is not a factor in trisomy 21 (nondisjunction) and mosaicism.
Can stress cause Down syndrome?
Down syndrome, which arises from a chromosome defect, is likely to have a direct link with the increase in stress levels seen in couples during the time of conception, say Surekha Ramachandran, founder of Down Syndrome Federation of India, who has been studying about the same ever since her daughter was diagnosed with …
Does folic acid prevent Down syndrome?
April 17, 2003 — Taking folic acid supplements before and during early pregnancy may not only help prevent neural tube defects in babies, but it may also reduce the risk of Down syndrome.